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Arthrosamid: The Revolutionary Long-Lasting Joint Injection

Arthrosamid is a groundbreaking non-biodegradable hydrogel injection providing long-lasting relief for knee osteoarthritis. Learn how it differs from other treatments.

Mr Kenan Dehne— Consultant Orthopaedic Surgeon7 min read6 April 2026

What is Arthrosamid?

Arthrosamid is an injectable non-biodegradable polyacrylamide hydrogel (iPAAG) that integrates permanently into the synovial membrane.

How It Works

Consisting of 2.5% cross-linked polyacrylamide and 97.5% water, it restores cushioning and reduces inflammation long-term.

Clinical Evidence

  • Significant pain reduction maintained at 2 and 4-year follow-up
  • Over 10,000 patients treated worldwide
  • No serious adverse events in clinical trials

Arthrosamid vs Other Injections

FeatureCorticosteroidHyaluronic AcidPRPArthrosamid
Duration6-12 weeks6-12 months12-18 months2-4+ years
SessionsSingleSingle3 sessionsSingle
Price£250£350£650 x3£3,200

Who is a Good Candidate?

Mild to moderate knee osteoarthritis (Kellgren-Lawrence grade 1-3) that hasn't responded to other treatments.

The Procedure

6ml injected under ultrasound guidance in approximately 20 minutes. Walk immediately, resume normal activities within 24 hours.

Cost and Value

At £3,200, when considering 2-4+ years of relief, it compares favourably to repeated courses of other injections.

arthrosamidkneeosteoarthritisinjectionhydrogel
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